CeRetrieve – Improved Stroke Intervention

  • Category: Medical Devices
  • Investment Status: Incubator
  • Medical Field: Other
  • Patent Status: PCT
  • Development Status: In development
  • Medical Center: Carmel Medical Center
  • Inventors: Dr. Ronen Jaffe

Ceretrieve’s aspiration catheter offers improved handling, enhanced clot aspiration, and improved retention of clots during removal. This Ceretrieve catheter is indicated for use in revascularization of patients with acute ischemic stroke and is compatible with current stent retrievers.

Technology: The use of mechanical devices to remove blood clots (thrombectomy) has become the standard of care for the treatment of acute ischemic stroke patients with large vessel occlusions. The purpose of these devices – stent retrievers and aspiration catheters – is to quickly extract clots, restore blood flow (revascularization), and achieve good clinical outcomes. Despite technological advances with current thrombectomy devices, successful revascularization is not always feasible (Neurosurgical Focus, 42:4, April 2017). Today, physicians are forced to choose between deploying expensive, cumbersome stent retrievers that may increase the risk of emboli release or taking a quicker approach: inserting aspiration catheters that are difficult to “steer” and advance through the arteries and have limited ability to provide efficient aspiration. According to Lawrence Biegelsen, a senior analyst at Wells Fargo Securities (“DAWN Trial Likely Positive for Stroke Market,” March 2017), in the United States alone there are over 290,000 ischemic stroke patients with large vessel occlusion. This number is expected to grow to >330,000 by 2021.There is great potential in this market as it is under-served. In 2016, only 23,000 stroke thrombectomy procedures were performed, with expected number of procedures to exceed 49,000 by 2021.